Multivariate analysis of associations between clinical sequencing and outcome in glioblastoma.
Peter H YangYu TaoJingqin R LuoMounica PaturuHsiang-Chih LuShakti RamkissoonJonathan W HeuselEric C LeuthardtMichael R ChicoineJoshua L DowlingGavin P DunnEric J DuncavageJeffrey R MillmanArindam R ChattherjeeAlbert H KimPublished in: Neuro-oncology advances (2022)
This study verifies the independent prognostic value of several mutant genes in glioblastoma. Six commonly found mutant genes were associated with improved survival when gross total resection was achieved. Thus, even when accounting for known predictors of survival and multiple mutant gene comparisons, extent of resection continues to be strongly associated with survival.