Characteristics of the sputum microbiome in COPD exacerbations and correlations between clinical indices.
Linfan SuYixian QiaoJinmei LuoRong HuangZhiwei LiHongbing ZhangHongmei ZhaoJing WangYi XiaoPublished in: Journal of translational medicine (2022)
Our study revealed variations in the sputum microbiome of AECOPD (based on composition and function) in a Chinese cohort and highlighted its correlation to clinical indices. These results indicated that microbial dysbiosis may contribute to disease progression and provide microbial biomarkers for the diagnosis of AECOPD.