In silico-guided engineering of Pseudomonas putida towards growth under micro-oxic conditions.

Linde F C KampersRuben G A van HeckStefano DonatiEdoardo SaccentiRita J M VolkersPeter J SchaapMaria Suarez-DiezPablo I NikelVitor A P Martins Dos Santos

Published in: Microbial cell factories (2019)

We demonstrated the value of combining in silico approaches, experimental validation and adaptive laboratory evolution for microbial design by making the strictly aerobic Pseudomonas putida able to grow under micro-oxic conditions.

Keyphrases

molecular docking
biofilm formation
microbial community
plant growth
high intensity
escherichia coli
pseudomonas aeruginosa
staphylococcus aureus