Optimization of the Diagnostic Capacity of Traditional Biomarkers in Muscle Damage and Its Use in the Diagnosis of Dermatomyositis and Polymyositis.
Sara Sanchez AsisMaría Cristina Gómez CoboDavid Ramos ChavarinoBeatriz García GarcíaIsabel Llompart AlbernJosé Antonio Delgado RodríguezPublished in: EJIFCC (2024)
The determination of CK offers a better diagnostic performance of MD and, in addition, does not present significant differences regarding the determination of aldolase in cases of polymyositis and dermatomyositis. Therefore, the single determination of CK would be sufficient for MD screening.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- solid phase extraction
- molecularly imprinted
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- molecular dynamics
- protein kinase
- disease activity
- skeletal muscle
- oxidative stress
- systemic lupus erythematosus
- simultaneous determination
- high resolution
- liquid chromatography
- tandem mass spectrometry