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Comparing lethal dose ratios using probit regression with arbitrary slopes.

Chengfeng LeiXiulian Sun
Published in: BMC pharmacology & toxicology (2018)
This procedure yielded accurate estimates of lethal doses and 95% CLs at different significance levels as well as the lethal dose ratios and 95% CLs between two examples. The procedure could be used to assess differences in the toxicities of two examples without the assumption of parallelism between probit-log(dose) regression lines.
Keyphrases
  • minimally invasive
  • high resolution
  • mass spectrometry