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Relationship of OCT-defined plaque characteristics with CCTA-derived coronary inflammation and CMR-derived global coronary flow reserve in patients with acute coronary syndrome.

Tomoyo SugiyamaYoshihisa KanajiMasahiro HoshinoMasahiro HadaToru MisawaTatsuhiro NagamineYun TengKai NogamiHiroki UenoKazuki MatsudaKodai SayamaEisuke UsuiTadashi MuraiTetsumin LeeTaishi YonetsuTetsuo SasanoTsunekazu Kakuta
Published in: PloS one (2023)
The presence of OCT-defined layered plaque at the culprit lesion was associated with high PCAT attenuation and low G-CFR after primary/urgent PCI in patients with ACS. OCT assessment of culprit plaque morphology and detection of layered plaque may help identify increased pericoronary inflammation and impaired CFR, potentially providing the risk stratification in patients with ACS and residual microvascular dysfunction after PCI.
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