Beyond sicca: high prevalence and predictors of baseline and worsening systemic involvement in patients with Sjögren's disease.
Matilde BandeiraManuel Silvério-AntónioNikita KhmelinskiiJoão E FonsecaVasco C RomãoPublished in: Rheumatology advances in practice (2024)
Systemic involvement is seen in most SS patients. Younger and RF and salivary gland biopsy-positive patients are at higher risk of systemic disease. Around half of patients with systemic involvement experienced aggravated disease over time, especially those with constitutional involvement or RF.