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Deregulated hypoxic response in myeloid cells: A model for high-altitude pulmonary oedema (HAPE).

Milos GojkovicGabriella S DarmasaputraPedro VeliçaHelene RundqvistRandall S Johnson
Published in: Acta physiologica (Oxford, England) (2020)
In this model, we show that a deregulated myeloid cell hypoxic response can trigger some of the most important symptoms of HAPE, and thus mice with a deletion of VHL in the myeloid lineage can function as a model of HAPE.
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