Clinical and epidemiological aspects of Candida yeast infections and rational use of antifungals.
Jose Moreira Neto JuniorVanessa Cordeiro DiasVictor Quinet de Andrad BastosLucas Quinet de Andrade BastosAndre Netto BastosRicardo Villela BastosVania Lucia SilvaAlessandra Barbosa Ferreira MachadoClaudio Galuppo DinizPublished in: Future microbiology (2024)
Aim: The objective of this study was to evaluate the clinical and epidemiological aspects of Candida infections. Methods: The study relied on the analysis of electronic medical records. Results: Among 183 patients with positive fungal infections, 57 were from the community and 126 from hospitals. Females predominated in both groups (82.4% in the community, 54.7% in hospitals). Non-albicans Candida spp. accounted for 62.8% of cases. Antifungal therapy was prescribed for 67 patients, with a 55.6% mortality rate. Conclusion: The increasing prevalence of non-albicans Candida species highlights the need for better candidiasis monitoring and control, especially concerning antifungal use amidst rising antimicrobial resistance, particularly in empirical therapy scenarios.