Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra (Ophiophagus hannah) venom via an alternative method.

Tuchakorn LertwanakarnMontamas SuntravatElda E SanchezWorakan BoonhohR John SolaroBeata M WolskaJody L MartinPieter P de Tombe Kittipong Tachampa

Published in: The journal of venomous animals and toxins including tropical diseases (2020)

We present an alternative purification method for β-CTX from king cobra venom. We reveal cytotoxicity towards smooth muscle and depression of cardiac contractility by this protein. These data are useful to aid future development of pharmacological agents derived from β-CTX.

Keyphrases

smooth muscle
klebsiella pneumoniae
depressive symptoms
electronic health record
genome wide
escherichia coli
angiotensin ii
single cell
big data
sleep quality
machine learning
physical activity
artificial intelligence
recombinant human
high glucose