Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study.

Marcello Henrique Araújo da Silva João Henrique Duque Estrada Bianca Martins Gregorio Francisco José Barcellos Sampaio Diogo Benchimol de Souza

Published in: Acta cirurgica brasileira (2021)

The 5-ARIs finasteride and dutasteride promoted morphological and functional damages in rat kidneys. In addition, rats in the dutasteride group showed more severe renal modifications than those in the finasteride group.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
oxidative stress
early onset
replacement therapy