Cathelicidin-related antimicrobial peptide mediates skeletal muscle degeneration caused by injury and Duchenne muscular dystrophy in mice.
Moon-Chang ChoiJiwon JoMyeongjin LeeJonggwan ParkTso-Pang YaoYoonkyung ParkPublished in: Journal of cachexia, sarcopenia and muscle (2022)
These findings identify Cramp as an immune cell-derived regulator of skeletal muscle degeneration and provide a potential therapeutic target for DMD.