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Facial changes related to brachycephaly in Cavalier King Charles Spaniels with Chiari-like malformation associated pain and secondary syringomyelia.

Susan Penelope KnowlerEleonore DumasMichaela SpiteriAngus K McFadyenFelicity StringerKevin WellsClare Rusbridge
Published in: Journal of veterinary internal medicine (2019)
CKCS with CM-P and SM-S have cranial brachycephaly with osseous insufficiency in the skull with rostral flattening and increased proximity of the hard and soft palate to the cranial base. Changes are greatest with CM-P. These findings have relevance for understanding disease pathogenesis and for selection of head conformation for breeding purposes.
Keyphrases
  • chronic pain
  • pain management
  • neuropathic pain
  • optic nerve
  • molecular dynamics simulations
  • crystal structure
  • postoperative pain