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High-resolution DNA content analysis of microbiopsy samples in oral lichen planus.

Monica PenteneroM MonticoneR MarinoC AielloG MarchittoD MalacarneW GiarettiS GandolfoP Castagnola
Published in: Oral diseases (2016)
DNA aneuploidy is an uncommon event in OLP and less frequent compared to other non-dysplastic and non-OLP oral potentially malignant disorders. The extremely low rate of DNA aneuploidy could represent an occasional finding or reflect the low rate of malignant transformation observed in patients with OLP even if the real prognostic value of DNA ploidy analysis in patients with OLP remains to be confirmed.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • high resolution
  • nucleic acid
  • mass spectrometry