Tumor and endothelial cell hybrids participate in glioblastoma vasculature.

Soufiane El HallaniCarole ColinYounas El HoufiAhmed IdbaïhBlandine BoisselierYannick MariePhilippe RavassardMarianne LabussièreKarima MokhtariJean-Léon ThomasJean-Yves DelattreAnne EichmannMarc Sanson

Published in: BioMed research international (2014)

A fraction of GBM stem cells thus has the capacity to fuse with endothelial cells and the resulting hybrids may participate in tumor microvascular proliferation and in treatment resistance.

Keyphrases

endothelial cells
stem cells
high glucose
signaling pathway
combination therapy
smoking cessation