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Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.

Youssef AfloukOumaima InoubliAmira KenzSaloua YacoubFerid ZaafraneLotfi GahaBesma Bel Hadj Jrad
Published in: Molecular biology reports (2023)
We suggest that TLR2-196-174Ins/Del and TLR6-S249P could be protective factors of females against BD. However, TLR2-R677W and TLR1-R80T could be strongly associated with higher risk of BD. Interestingly, TLR2-R677W could be a genetic marker for BD in females. However, further studies with larger groups are needed to confirm these findings.
Keyphrases
  • toll like receptor
  • inflammatory response
  • immune response
  • bipolar disorder