Validation of a method to assess emphysema severity by spirometry in the COPDGene study.

Mariaelena OcchipintiMatteo PaolettiJames D CrapoBarry J MakeDavid A LynchVito BrusascoFederico LavoriniEdwin K SilvermanElizabeth A ReganMassimo Pistolesi

Published in: Respiratory research (2020)

ESI adds to standard spirometry the power to discriminate whether emphysema is the predominant mechanism of airway obstruction. ESI methodology has been validated in the large multiethnic population of smokers of the COPDGene study and therefore it could be applied for clinical and research purposes in the general population of smokers, using a readily available online website.

Keyphrases

lung function
ms ms
chronic obstructive pulmonary disease
smoking cessation
healthcare
health information
air pollution