vLUME: 3D virtual reality for single-molecule localization microscopy.

Alexander SparkAlexandre KitchingDaniel Esteban-FerrerAnoushka HandaAlexander R CarrLisa-Maria NeedhamAleks PonjavicAna Mafalda SantosJames McCollChristophe LeterrierSimon J DavisRicardo HenriquesSteven F Lee

Published in: Nature methods (2020)

vLUME is a virtual reality software package designed to render large three-dimensional single-molecule localization microscopy datasets. vLUME features include visualization, segmentation, bespoke analysis of complex local geometries and exporting features. vLUME can perform complex analysis on real three-dimensional biological samples that would otherwise be impossible by using regular flat-screen visualization programs.

Keyphrases

single molecule
virtual reality
living cells
atomic force microscopy
deep learning
public health
high throughput
convolutional neural network
machine learning
optical coherence tomography