Glucuronides of phytoestrogen flavonoid enhance macrophage function via conversion to aglycones by β-glucuronidase in macrophages.
Atsushi KanekoTakashi MatsumotoYosuke MatsubaraKyoji SekiguchiJunichi KosekiRyo YakabeKatsuyuki AokiSetsuya AibaKenshi YamasakiPublished in: Immunity, inflammation and disease (2017)
This study suggests a molecular mechanism by which oral flavonoids are carried as glucuronides and activated to aglycones by β-glucuronidase in tissue macrophages, and contributes to the pharmacological study of glucuronides.
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