Maximal exercise increases mucosal associated invariant T cell frequency and number in healthy young men.
Erik D HansonEli DansonCatriona V Nguyen-RobertsonJackson J FyfeNigel K SteptoDavid B BartlettSamy SakkalPublished in: European journal of applied physiology (2017)
Maximal exercise doubled MAIT cell numbers and showed preferential mobilization within total T cells but the response was not influenced by fitness levels, exercise duration, or body composition. These results suggest that acute exercise could be used to offset MAIT cell deficiencies observed with certain pathologies. MAIT cells also make up a substantial proportion of CTLs, which may have implications for cytotoxicity assays using these cells.
Keyphrases
- resistance training
- body composition
- high intensity
- induced apoptosis
- physical activity
- cell cycle arrest
- bone mineral density
- single cell
- cell therapy
- liver failure
- high throughput
- middle aged
- cell death
- intensive care unit
- signaling pathway
- mesenchymal stem cells
- postmenopausal women
- hepatitis b virus
- respiratory failure
- drug induced
- acute respiratory distress syndrome