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Extranodal NK/T cell lymphoma, nasal type: a rare diagnosis with common nasal presentation.

Siti Sarah Mohd RamliSalina HusainYin Ping Wong
Published in: BMJ case reports (2021)
A 39-year-old man presented with bilateral nasal obstruction for 4 months and associated with hyposmia and foul-smelling nasal discharge. Nasal endoscopy showed irregular mucosa of the nasal cavity with easily bleeding. Nasal biopsy reported as extranodal Natural Killer/T cell lymphoma, nasal type. In-situ hybridisation for Epstein-Barr encoding region was positive. He was treated with six cycles of gemcitabine, oxaliplatin and L-asparaginase and peripheral blood stem cell transplant. After the treatment, he was asymptomatic until 9 months where he had splenic abscess and undergone splenectomy. He was asymptomatic of the disease for 2 years.
Keyphrases
  • chronic rhinosinusitis
  • stem cells
  • peripheral blood
  • atrial fibrillation
  • case report
  • bone marrow
  • rectal cancer
  • locally advanced
  • newly diagnosed
  • rare case