Humanin gene expression in subjects with Parkinson's disease.

Michele SalemiFederico RidolfoMaria Grazia SalluzzoFrancesca A SchillaciSalvatore CanigliaBartolo LanuzzaMariagiovanna CantoneRaffaele Ferri

Published in: Molecular biology reports (2023)

In conclusion, the present data confirm the tendency of mitochondria to overexpress mRNA in PD, which could be a cellular attempt to reduce apoptotic damage in PD subjects. Humanin might be useful as a marker for a better diagnosis of PD, and we cannot exclude that in the future it might also play a role on prognosis and in the possible therapies for PD.

Keyphrases

gene expression
cell death
oxidative stress

dna methylation
electronic health record

big data
machine learning

deep learning
artificial intelligence