Systemic proinflammation after Mycobacterium tuberculosis infection was correlated to the gut microbiome in HIV-uninfected humans.
Shiang-Fen HuangYing-Ying YangKun-Ta ChouChang-Phone FungFu-Der WangWei-Juin SuPublished in: European journal of clinical investigation (2019)
In active TB, dysbiosis with higher relative abundances of Bacteroidetes in stool and low F/B ratio was related to systemic proinflammation. In LTBI, dose-response relationship between peripheral PMN and relative abundances of Bacteroidetes was remained but not leads to systemic inflammation.