Dexamethasone versus Surgery for Chronic Subdural Hematoma.
Ishita P MiahDana C HollJurre BlaauwHester F LingsmaHeleen M den HertogBram JacobsNyika D KruytJoukje van der NaaltSuzanne PolinderRob J M GroenKuan H KhoFop van KootenClemens M F DirvenWilco C PeulKorné JellemaRuben DammersNiels A van der Gaagnull nullPublished in: The New England journal of medicine (2023)
In a trial that involved patients with chronic subdural hematoma and that was stopped early, dexamethasone treatment was not found to be noninferior to burr-hole drainage with respect to functional outcomes and was associated with more complications and a greater likelihood of later surgery. (Funded by the Netherlands Organization for Health Research and Development and others; DECSA EudraCT number, 2015-001563-39.).