Integrative analysis reveals a lineage-specific circular RNA landscape for adipo-osteogenesis of human mesenchymal stem cells.

Hai-Bo HuangHai-Tao LuoNa-Na WeiMiao-Ling LiuFei HeWei YangJun DongXiao-Fei YangFu-Rong Li

Published in: Stem cell research & therapy (2022)

Our integrative analysis reveals an accurate and generally applicable lineage-specific circRNA landscape for adipo-osteogenesis of MSCs and provides a potential therapeutic target, circ-CRLF1, for the treatment of skeleton-related disease.

Keyphrases

mesenchymal stem cells
single cell
umbilical cord
endothelial cells
bone marrow
network analysis
high resolution
induced pluripotent stem cells
stem cells