Construction of a recombinant avipoxvirus expressing the env gene of Zika virus as a novel putative preventive vaccine.
Carlo ZanottoFrancesca PaoliniAntonia RadaelliCarlo De Giuli MorghenPublished in: Virology journal (2021)
Although BALB/c mice appear to be an adequate model for ZIKV infection, as it mimics the natural mild infection in human beings, inadequate immune suppression seemed to occur by dexamethasone and different immune suppression strategies should be applied before challenge to reveal any protection of the mice.