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Elevated α-defensin levels in plasma and bronchoalveolar lavage fluid from patients with myositis-associated interstitial lung disease.

Noriho SakamotoHiroshi IshimotoTomoyuki KakugawaMinoru SatohTomoko HasegawaShin TanakaAtsuko HaraShota NakashimaHirokazu YuraTakuto MiyamuraHanako KoyamaTowako MoritaSeiko NakamichiYasushi ObaseYuji IshimatsuHiroshi Mukae
Published in: BMC pulmonary medicine (2018)
Plasma and BALF HNPs might reflect the disease activities of myositis-associated ILD, especially in patients with anti-ARS antibody positive myositis-associated ILD. However further studies are necessary to clarify whether HNPs represent disease markers and play roles in disease pathogenesis.
Keyphrases
  • interstitial lung disease
  • systemic sclerosis
  • rheumatoid arthritis
  • idiopathic pulmonary fibrosis