APRIL and BAFF: novel biomarkers for central nervous system lymphoma.

Matthias MulazzaniMarion HuberSabine BorchardSigrid LangerBarbara AngeleElisabeth SchuhEdgar MeinlMartin DreylingTobias BirnbaumAndreas StraubeUwe KoedelLouisa von Baumgarten

Published in: Journal of hematology & oncology (2019)

This study extends the spectrum of valuable diagnostic biomarkers in CNSL. In patients with focal brain lesions, measurement of APRIL in CSF could help accelerating the diagnosis of CNSL. Moreover, our results highlight an important role of APRIL and BAFF in the pathophysiology of CNSL.

Keyphrases

cerebrospinal fluid
diffuse large b cell lymphoma
brain injury