Does weight mediate the effect of smoking on coronary heart disease? Parametric mediational g-formula analysis.

Yaser MokhayeriMaryam NazemipourMohammad Ali MansourniaAshley I NaimiJay S Kaufman

Published in: PloS one (2022)

The overall absolute impact of smoking to incident coronary heart disease is modest, and we did not discern any important contribution to this effect relayed through changes to bodyweight. In fact, changes in weight because of smoking have no meaningful mediating effect on CHD risk.

Keyphrases

smoking cessation
body mass index
weight loss
physical activity
type diabetes
body weight
human milk