Vertebroplasty as a palliative treatment option for intractable pain in pediatric patients with spinal tumors.
Leandro Cardarelli-LeiteShahrad Rod RassekhRobert D'OrtenzioManraj Kanwal Singh HeranPublished in: Pediatric blood & cancer (2021)
Primary and secondary malignant tumors of the spine are relatively uncommon in the pediatric population but are associated with high morbidity and significantly decreased quality of life due to pain. Local management of these tumors is often challenging due to the importance of maintaining vertebral mechanical integrity as well as the spinal growth potential. Typically, surgery and/or radiation therapy have been used in the primary management of these tumors. However, treatment options become more limited when there is relapse or refractory disease, with re-resection or additional radiotherapy often not being viable therapies. Vertebroplasty is a currently underutilized modality that might provide significant pain palliation in cases of relapsed cancer in the spine.
Keyphrases
- chronic pain
- radiation therapy
- pain management
- neuropathic pain
- spinal cord
- minimally invasive
- acute lymphoblastic leukemia
- acute myeloid leukemia
- early stage
- locally advanced
- coronary artery bypass
- radiation induced
- multiple myeloma
- young adults
- squamous cell carcinoma
- palliative care
- body composition
- spinal cord injury
- bone mineral density
- hodgkin lymphoma
- papillary thyroid
- rectal cancer
- postmenopausal women
- combination therapy
- postoperative pain
- squamous cell