Metronidazole and amoxicillin for patients with periodontitis and diabetes mellitus: 5-year secondary analysis of a randomized controlled trial.

Daniele Ferreira da CruzPoliana Mendes DuarteLuciene Cristina FigueiredoHélio Doyle Pereira da SilvaBelén Retamal-ValdesMagda FeresTamires Szeremeske de Miranda

Published in: Journal of periodontology (2020)

Diabetic patients treated with adjunctive MTZ+AMX were better maintained over a period of 5 years than those treated with SRP only. However, the clinical and microbiological benefits obtained up to 2 years post-treatment were not fully sustained in these patients who did not receive SPT between 2 and 5 years post-treatment.

Keyphrases

type diabetes
combination therapy
metabolic syndrome
insulin resistance
skeletal muscle
glycemic control
weight loss