Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury.
Kevin Y SteinLogan FroeseAlwyn GomezAmanjyot Singh SainbhiNuray VakitbilirYounis IbrahimAbrar IslamIzabella MarquezFiorella AmentaTobias BergmannFrederick Adam ZeilerPublished in: Intensive care medicine experimental (2023)
Our study supports the existing narrative that time spent with CPP below CPPopt results in poorer outcomes. However, it also suggests that time spent above CPPopt may not be associated with worse outcomes and is possibly even associated with improvement in outcome.