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Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats.

Songyan YuYu ChengLinxi ZhangYaqi YinJing XueBing LiZhengyuan GongJieqing GaoYi-Ming Mu
Published in: Stem cell research & therapy (2019)
Multiple intravenous infusions of ADSCs produced significant protective effects against long-term T2DM complications by alleviating inflammation and promoting tissue repair. The present study suggests ADSCs may be a novel, alternative cell therapy for long-term diabetic complications.
Keyphrases
  • adipose tissue
  • oxidative stress
  • risk factors
  • type diabetes
  • stem cells
  • high dose
  • high fat diet
  • skeletal muscle
  • glycemic control
  • combination therapy
  • weight loss
  • smoking cessation
  • replacement therapy