A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study).

Belén Ruiz-AntoranAranzazu Sancho-LópezRosario Cazorla-CallejaLuis Fernando López-PájaroÁgata LeivaGema Iglesias-EscaleraMaria Esperanza Marín-SerranoMarta Rincón-OrtegaJulián Lara-HerguedasTeresa Rossignoli-PalomequeSara Valiente-RodríguezJavier González-MarquesEnriqueta Román-RiechmannCristina Avendaño-Solá

Published in: Orphanet journal of rare diseases (2018)

European Clinical Trial database ( EudraCT 2013-002154-67 ), registered 16th September 2013; US Clinical trials database ( NCT02056665 ), registered 6th February 2014.

Keyphrases

clinical trial
double blind
phase ii
placebo controlled
phase iii
study protocol
open label
case report
squamous cell carcinoma
emergency department
radiation therapy