Leptin Supplementation During Lactation Restores Key Liver Metabolite Levels Malprogrammed by Gestational Calorie Restriction.

Zhi Xin Yau-QiuFrancisco Madrid-GambinLorraine BrennanAndreu PalouAna María Rodríguez

Published in: Molecular nutrition & food research (2021)

Physiological leptin supplementation during lactation contributes to the reversion of changes caused by maternal mild calorie restriction on the liver metabolome. This agrees with a putative role of leptin supplementation preventing or reversing metabolic disturbances caused by gestational metabolic malprogramming.

Keyphrases

weight gain
birth weight
pregnant women
pregnancy outcomes
human milk
weight loss
dairy cows
gestational age