Case report: malignant hypertension associated with catecholamine excess in a patient with Leigh syndrome.
Ana SolisJoshua ShimonyMarwan ShinawiKevin T BartonPublished in: Clinical hypertension (2023)
Elevated catecholamines with malignant secondary hypertension may be unique to this specific mutation or may be a previously unrecognized feature of Leigh syndrome and other mitochondrial complex I deficient syndromes. As such, patients with Leigh syndrome who present with malignant hypertension should be treated without the need for extensive work-up for catecholamine-secreting tumors.