Development of a strategic approach for comprehensive detection of organophosphate pesticide metabolites in urine: Extrapolation of cadusafos and prothiofos metabolomics data of mice to humans.
Karin NomasaNaoko OyaYuki ItoTakehito TerajimaTakahiro NishinoNayan Chandra MohantoHirotaka SatoMotohiro TomizawaMichihiro KamijimaPublished in: Journal of occupational health (2021)
Our developed method successfully identified prothiofos metabolites that are usually not a target of biomonitoring studies. Our approach is extensively applicable to various environmental contaminants beyond OP pesticides.
Keyphrases
- ms ms
- risk assessment
- human health
- mass spectrometry
- multidrug resistant
- electronic health record
- high fat diet induced
- drinking water
- loop mediated isothermal amplification
- big data
- case control
- label free
- real time pcr
- gas chromatography
- insulin resistance
- life cycle
- artificial intelligence
- high resolution
- climate change