Interlaboratory Gleason grading variation affects treatment: a Dutch historic cohort study in 30 509 patients with prostate cancer.

Rachel N FlachCarmen van DooijeweertKatja K H AbenBritt B M SuelmannPeter-Paul M WillemsePaul J van DiestRichard P Meijer

Published in: Journal of clinical pathology (2022)

Our study shows that the odds that a patient undergoes AT or PLND, depends on laboratories' grading practices in a substantial number of patients. This likely influences patient prognosis and outcome, necessitating standardisation of GG to prevent suboptimal patient outcome.

Keyphrases

prostate cancer
case report
end stage renal disease
radical prostatectomy
newly diagnosed
healthcare
ejection fraction
chronic kidney disease
primary care
prognostic factors
peritoneal dialysis
combination therapy
patient reported outcomes
replacement therapy