Solving the mystery of HBV-related mixed cryoglobulinemia: potential biomarkers of disease progression.

Krizia PocinoCecilia NapodanoLaura GragnaniGabriele CiascaStefania ColantuonoSilvia MarriLorenzo VantaggioFrancesca GulliSerena LoriniAntonella BariniAnnunziata StefanileLuca MieleMilvia CasatoAnna Linda ZignegoGian Ludovico RapacciniMariapaola MarinoMarcella VisentiniUmberto Basile

Published in: Rheumatology (Oxford, England) (2021)

The immune-inflammatory response triggered by HBV may be monitored by a peculiar profile of biomarkers. Our results open a new perspective in the precision medicine era; in these challenging times, they could also be employed to monitor the clinical course of those COVID-19 patients who are at high risk of HBV reactivation due to liver impairment and/or immunosuppressive therapies.

Keyphrases

hepatitis b virus
inflammatory response
liver failure
sars cov
minimally invasive
lipopolysaccharide induced
lps induced