GOLPH3 promotes glioma progression via facilitating JAK2-STAT3 pathway activation.

Shishuang WuJiale FuYu DongQinghao YiDong LuWeibing WangYanhua QiRutong YuXiu-Ping Zhou

Published in: Journal of neuro-oncology (2018)

GOLPH3 may act as a scaffold protein to regulate JAK2-STAT3 interaction and then its activation, which therefore mediates the effect of GOLPH3 on cell proliferation.

Keyphrases

cell proliferation
cell cycle
protein protein
binding protein
tissue engineering