Exact solving and sensitivity analysis of stochastic continuous time Boolean models.
Mihaly KoltaiVincent NoelAndrei ZinovyevLaurence CalzoneEmmanuel BarillotPublished in: BMC bioinformatics (2020)
Up to an intermediate size (the biggest model analyzed is 23 nodes) stochastic Boolean models can be efficiently solved by an exact matrix method, without using Monte Carlo simulations. Sensitivity analysis with respect to the model's timescale parameters often reveals a small subset of all parameters that primarily determine the stationary probability of attractor states.