Visual Sequence Encoding is Enhanced by Predictable Music Pairing via Modulating Medial Temporal Lobe and Its Connectivity with Frontostriatal Loops.

There is considerable interest in what mechanisms can be tapped to improve human memory. Music provides a potential modulator, but few studies have investigated music effects on encoding episodic memory. This study used a novel design to examine how music can influence concurrent visual item sequence encoding. We provided neural data to better understand mechanisms behind potential benefits of music for learning. Our results demonstrated predictable music may help guide parallel learning of sequences in another modality. We found that music might facilitate processing in neural systems associated with visual declarative long-term and working memory, and familiar music might modulate reward circuits and provide a temporal schema which facilitates better encoding of the temporal structure of new non-music information.