TRIM31 and ELF3 may be the two hub genes in urothelium corresponding to IC/BPS. More studies are warranted to further validate the findings. The identified marker genes may be useful targets for further studies to develop diagnostic tools and more effective therapies for a broader group of women with IC/PBS.
Keyphrases
- bioinformatics analysis
- lipopolysaccharide induced
- genome wide
- inflammatory response
- induced apoptosis
- endothelial cells
- genome wide identification
- spinal cord injury
- genome wide analysis
- dna methylation
- oxidative stress
- urinary tract
- gene expression
- signaling pathway
- cell death
- induced pluripotent stem cells
- network analysis