Genetically Predicted Differences in Systolic Blood Pressure and Risk of Cardiovascular and Noncardiovascular Diseases: A Mendelian Randomization Study in Chinese Adults.
Robert J ClarkeNeil WrightRobin G WaltersWei GanYu GuoIona Y MillwoodLing YangYiping ChenSarah LewingtonJun LvCanqing YuDaniel AveryKuang LinKang WangRichard PetoRory CollinsLiming LiDerrick A BennettSarah ParishZhengming Chennull nullPublished in: Hypertension (Dallas, Tex. : 1979) (2023)
The findings provide support for initiation of blood pressure-lowering treatment at younger ages and below the conventional cut-offs for hypertension to maximize CVD prevention, albeit the absolute risks of CVD are far greater in older people.