Login / Signup

CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin.

Kunzhe DongJian ShenXiangqin HeGuoqing HuLiang WangIslam OsmanKristopher M BuntingRachael Dixon-MelvinZeqi ZhengHong-Bo XinMeixiang XiangAlmira VazdarjanovaDavid J R FultonJiliang Zhou
Published in: Circulation (2021)
CARMN is an evolutionarily conserved SMC-specific long noncoding RNA with a previously unappreciated role in maintaining the contractile phenotype of VSMCs and is the first noncoding RNA discovered to interact with myocardin.
Keyphrases
  • smooth muscle
  • long noncoding rna
  • transcription factor
  • skeletal muscle
  • single cell
  • cell therapy
  • stem cells
  • bone marrow
  • nucleic acid