Description of an activity-based enzyme biosensor for lung cancer detection.
Paul W DempseyCristina-Mihaela SanduRicardo GonzaleziriasSpencer HantulaObdulia Covarrubias-ZambranoStefan H BossmannAlykhan S NagjiNirmal K VeeramachaneniNezih O ErmerakDerya KocakayaTunc LacinBedrittin YildizeliPatrick LilleySara Witting Christensen WenLine NederbyTorben F HansenOle HilbergPublished in: Communications medicine (2024)
This approach is promising as a scalable, clinically useful platform to help detect patients who have lung cancer using a simple blood sample. The performance and cost profile is being pursued in studies as a platform for population wide screening.