Successful liver transplantation in patients with active SARS-CoV-2 infection.
Charles A MouchSophoclis P AlexopoulosRichard W LaRueHannah P KimPublished in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2022)
The Coronavirus Disease 2019 (COVID-19) pandemic has substantially impacted solid organ transplantation, including temporary inactivation of waitlist candidates with COVID-19 infection. We report two cases of liver transplantation (LT) in individuals with asymptomatic COVID-19 infection. The first patient is a 68-year-old female with decompensated cirrhosis complicated by worsening frailty and sarcopenia. The second patient is a 22-year-old female with acute liver failure likely secondary to drug/toxin exposure. Both patients were treated with COVID-19-directed therapies and neither patient developed symptomatic disease. These cases demonstrate that LT can be safely performed in select patients with asymptomatic COVID-19 infection at the time of transplant.
Keyphrases
- liver failure
- coronavirus disease
- case report
- hepatitis b virus
- newly diagnosed
- ejection fraction
- end stage renal disease
- heart failure
- respiratory syndrome coronavirus
- sars cov
- chronic kidney disease
- skeletal muscle
- prognostic factors
- respiratory failure
- intensive care unit
- atrial fibrillation
- extracorporeal membrane oxygenation