Effects of local and systemic treatment with human natural killer-1 mimetic peptide (HNK-1) after ventral root avulsion and reimplantation in mice.
Natalia Scanavachia da SilvaJulia LombardiFrank KirchhoffRui Seabra Ferreira JúniorBenedito BarravieraAlexandre Leite Rodrigues de OliveiraLuciana Politti CartarozziPublished in: The journal of venomous animals and toxins including tropical diseases (2024)
Overall, the results indicate that UA is neuroprotective, acting on glial cells and synaptic maintenance, and the combination of these findings led to a better functional recovery.
Keyphrases
- induced apoptosis
- endothelial cells
- spinal cord
- cell cycle arrest
- prefrontal cortex
- induced pluripotent stem cells
- high fat diet induced
- neuropathic pain
- endoplasmic reticulum stress
- spinal cord injury
- cerebral ischemia
- skeletal muscle
- insulin resistance
- combination therapy
- replacement therapy
- drug induced
- wild type