Efficacy, Outcome, and Safety of Elderly Patients with Glioblastoma in the 5-ALA Era: Single Center Experience of More Than 10 Years.
Barbara KieselLisa Irina WadiuraMario MischkulnigJessica MakolliVeronika SperlMartin BorkovecJulia FreundAlexandra LangMatthias MillesiAnna S BerghoffJulia FurtnerAdelheid WöhrerGeorg WidhalmPublished in: Cancers (2021)
Our data of this large elderly cohort demonstrate the clinical utility and safety of 5-ALA fluorescence in GBM for improved tumor visualization in both resections as well as biopsies. Therefore, we recommend the use of 5-ALA not only in resections, but also in open/stereotactic biopsies to optimize the neurosurgical management of elderly GBM patients.