A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies.

Maribel Aranda-GuillénEllen Christine RøyrvikSara Fletcher-SandersjööHaydee ArtazaIleana Ruxandra BotusanMarianne A GrytaasÅsa HallgrenLars BreivikMaria PetterssonAnders P JørgensenAnna LindstrandElinor Vogtnull nullEystein S HusebyeOlle KämpeAnette S Bøe WolffSophie BensingStefan JohanssonDaniel Eriksson

Published in: Journal of internal medicine (2023)

The PRS performed well for case-control differentiation and susceptibility estimation in individual patients. Remarkably, a PRS for AAD holds promise as a means to detect disease etiologies other than autoimmunity.

Keyphrases

end stage renal disease
case control
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
big data
patient reported outcomes
artificial intelligence
patient reported